ICD code S59.221S – Salter-Harris Type II distal radius fracture, sequela
Billable Code Specific Code
S59.221S is the billable ICD-10-CM code for Salter-Harris Type II physeal fracture of lower end of radius, right arm, sequela.
The "S" seventh character signals that the visit is for a residual condition caused by that fracture, not for the fracture itself. A common cause of sequela denials is sequencing S59.221S ahead of the residual condition code. Another is keeping the "A" or "D" character after active fracture care has ended.
- Chapter
- S00-T88 Injury, poisoning and certain other consequences of external causes
- Category
- S59 Other and unspecified injuries of elbow and forearm
- Group
- S59.221 Salter-Harris Type II physeal fracture of lower end of radius, right arm
- Billable
- Yes
- Code also known as
- growth plate fracture sequela, distal radius physeal fracture late effect, wrist growth plate fracture complication
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Key takeaways
S59.221S describes the long-term residual effects of a Salter-Harris Type II fracture at the distal radius physis, not the acute fracture encounter.
The residual condition code is sequenced first, and S59.221S follows it as the causal code.
Seventh characters G, K and P cover delayed healing, nonunion and malunion while the fracture is still under treatment.
Common denial triggers include wrong character (A or D), missing fracture history in the record, and laterality mismatch.
Pabau, our practice management platform, keeps the clinical note and the claim on one patient record.
ICD-10 Code S59.221S: Full descriptor and code structure
ICD-10 Code S59.221S is the billable code for the sequela of a Salter-Harris Type II fracture of the right distal radius. It is reported for a residual condition left by that fracture, once active fracture treatment has ended.
ICD-10 Code S59.221S sits in Chapter 19 of ICD-10-CM, which covers injury, poisoning and certain other consequences of external causes. Its category is S59, other and unspecified injuries of the elbow and forearm. The subcategory S59.22 covers Salter-Harris Type II physeal fractures of the distal radius specifically, with the seventh character “S” completing the code to indicate sequela.
According to the CDC/NCHS ICD-10-CM official web tool, S59.221S is a valid, billable code for the current fiscal year. Coders can verify the full tabular hierarchy and any annual updates directly through that tool before submitting claims.
Understanding the seventh character “S” and sequela coding
The seventh character “S” in ICD-10-CM denotes a sequela encounter. The patient is treated for a condition caused by a prior injury, after that injury’s active healing phase has ended. Sequela is not the same as a subsequent encounter (character “D”), which still involves active healing of the original fracture.
Malunion has a seventh character of its own. Report S59.221P while the malunion is still being treated as part of the fracture episode. S59.221S applies once fracture care has ended and the visit is for a lasting consequence of the injury.
Per the ICD-10-CM Official Guidelines for Coding and Reporting (Sections I.B.10 and I.C.19.a), the sequela code is sequenced after the code describing the residual condition. The residual condition is what the patient is being seen for, and ICD-10 Code S59.221S is the causal explanation.
Clinical context: Salter-Harris Type II fracture of the distal radius
Salter-Harris Type II is the most common physeal fracture type in children. Pediatric orthopedic literature puts it at roughly 75% of all growth plate fractures. The fracture passes through the physis and exits through a metaphyseal fragment, leaving the epiphysis intact.
The distal radius physis is the most frequently injured growth plate in children, typically from a fall on an outstretched hand (FOOSH mechanism). Most acute fractures heal without complication. However, a subset of patients develop sequelae that require ongoing clinical attention.
- Growth arrest: partial or complete physeal closure causing limb length discrepancy or angular deformity
- Malunion: the fracture healed in a position outside acceptable alignment, causing functional impairment
- Posttraumatic wrist stiffness: restricted range of motion persisting beyond the healing phase
- Ulnar variance change: altered radial length relative to the ulna, affecting wrist mechanics
Each of these conditions can support ICD-10 Code S59.221S as the causal sequela code. The record must document it as a direct consequence of the prior Salter-Harris Type II fracture. The residual condition is coded first, using codes such as M21.xx for angular deformity or M89.1x for epiphyseal arrest.
Laterality variants and related S59.221 codes
Laterality is required for S59.221S. Using the unspecified code (S59.229S) when the record documents a side is a documentation error. It can trigger a denial or a request for more information.
The diagnostic codes library carries a full reference page for each of these neighboring codes, with the same sequencing and documentation notes. Checking the neighbor before assigning S59.221S takes less time than reworking the claim.
Sequencing rules: Coding S59.221S correctly
The ICD-10-CM Official Guidelines for Coding and Reporting require a specific sequencing order for all sequela encounters. Reversing that order is the leading cause of sequela claim denials. Sound medical billing compliance starts with getting the code order right on every claim.
- Code the residual condition first. Assign the ICD-10-CM code that describes what the patient is currently being treated for. Examples are M21.xx (angular deformity), M89.1x (epiphyseal arrest, for growth arrest at the physis) and M89.8x (other specified disorders of bone). Malunion is not coded here. Report it with the seventh character P (S59.221P) rather than an M84.33x stress fracture code.
- Follow with ICD-10 Code S59.221S. Place the sequela code second, identifying the prior Salter-Harris Type II distal radius fracture as the cause of the current condition.
- Do not revert to character A or D once the fracture is in the sequela stage. Using S59.221A or S59.221D for the same injury misrepresents the encounter type to the payer.
- Verify laterality matches the record. S59.221S is right-sided. If the documented injury is left-sided, S59.222S is correct.
In practice, that order produces a claim line with three layers.

The CMS ICD-10-CM coding guidelines and update files are the primary reference for sequela sequencing rules. Coders should review Sections I.B.10 and I.C.19.a each fiscal year, as guidance may be refined in annual updates.
Documentation requirements for S59.221S
A sequela claim has to show, in the record, that a current condition follows from an injury treated earlier. Five elements must be present to support ICD-10 Code S59.221S.
- Prior fracture history: documentation (operative report, imaging, prior visit note) confirming the patient sustained a Salter-Harris Type II fracture of the distal radius physis
- Residual condition identification: the current note must name the specific residual condition (growth arrest, angular deformity, stiffness) that prompted this visit
- Causal link: the record must show that the current condition results from the prior fracture rather than a new injury or unrelated pathology
- Laterality: the affected side (right or left) must be specified in the note; do not default to unspecified when the information is available
- Sequencing confirmation: the residual condition code is listed first on the claim; S59.221S appears as the secondary or tertiary code
A documentation checklist sitting in the billing queue catches missing elements before the claim is transmitted. Most claims management software can attach that checklist to the claim, so the coder sees what is still outstanding.

Common claim denial reasons and how to avoid them
Sequela claims fail for a short list of recurring reasons, and each one is preventable at the coding desk. Effective denial management depends on knowing those patterns and building a check for each before the claim is submitted.
Denial volume also drops when the first attempt is a clean claim. That means complete patient demographics, the correct payer ID, and every required secondary code in place before the claim leaves the system. One missing field on a sequela claim often triggers a blanket medical necessity denial rather than a request to correct the data.
Pro Tip
Run a two-field check before submitting any S59.221S claim. Confirm the residual condition code is in position 1, then verify the code’s laterality against the side documented in today’s note. Those two steps catch most sequela denials at the source.
Payer requirements and prior authorization
Medicare does not require prior authorization for evaluation and management visits or for most diagnostic imaging when billed with S59.221S. Medical necessity documentation is still required on every claim, and the usual medical billing standards apply whatever the payer.
- Surgical correction (e.g., osteotomy for malunion): most commercial payers require prior authorization. Submit the operative plan, imaging confirming the deformity, and functional assessment documentation with the authorization request.
- Physical or occupational therapy: many plans require a therapy authorization for sequela-related rehabilitation. Obtain this before the first therapy visit, not after.
- Imaging (X-ray, CT): generally covered without prior auth for Medicare; commercial plans vary. Check payer-specific policies by CPT code before ordering advanced imaging.
- Local Coverage Determinations (LCDs): Medicare Administrative Contractor (MAC) jurisdictions may have LCDs governing coverage for physeal fracture sequelae management. Verify with the applicable MAC before billing.
Payer requirements for surgical sequelae correction vary by plan year and carrier. Verify individual payer policies directly rather than relying on prior authorization decisions from previous plan years.
CPT codes commonly paired with S59.221S
The CPT codes submitted alongside ICD-10 Code S59.221S depend on what is being done at the current visit. Pairings run from evaluation and management visits through to surgical osteotomy for malunion correction. Physical therapy practices treating sequela-related wrist stiffness often bill this diagnosis alongside therapy evaluation codes.
CPT pairing decisions affect claim adjudication. A clearinghouse validates the CPT-to-ICD-10 pairing before the claim reaches the payer, which is where a mismatched osteotomy code gets caught. Pabau’s US clearinghouse partner is Claim.MD, and how Claim.MD works covers eligibility verification, 837P submission and ERA remittance in detail.
Practices billing an osteotomy CPT code with S59.221S list the residual condition as the primary diagnosis. The note must also document the functional impairment that makes surgical correction medically necessary. A superbill carrying all three code layers tends to process more cleanly on first pass.
Inclusion and exclusion notes in the tabular list
The ICD-10-CM tabular list provides inclusion and exclusion annotations that define the code’s boundaries. Coders should review these before assigning S59.221S to avoid crossover errors.
- Included: sequela of Salter-Harris Type II physeal fractures at the distal radial physis, the growth plate at the wrist end of the radius
- Not included in S59.221S: Salter-Harris Type I fractures of the distal radius physis (use S59.211S), Type III (S59.231S), or Type IV (S59.241S)
- Not included: physeal fractures of the distal ulna (use the S59.0xx series, physeal fracture of lower end of ulna)
- Not included: fractures of the radial shaft or proximal radius (different S-category codes)
Verify the specific Salter-Harris type documented in the original operative or imaging report before assigning S59.221S. A Type I or Type III injury documented at the original fracture requires a different sequela code, even at the same distal radius site.
How Pabau supports sequela documentation and claim accuracy
Sequela coding breaks down when the note and the claim live in separate systems. The coder then rebuilds the laterality, the original fracture type and the residual condition from whatever was copied across.
Pabau keeps both on the same patient record. Clinical notes, imaging reports and invoices sit against one patient, so the detail a sequela claim needs is already in front of the coder.
- The clinical note and the claim sit on one patient record, so laterality and fracture history are read from the chart
- Claims are reviewed before submission through the Claim.MD integration, so pairing and sequencing problems surface while they can still be fixed
- Native integrations are included in every subscription, so claim review is not a paid add-on for a smaller practice
For a practice billing sequela codes regularly, the rework loop gets shorter. Fewer claims come back, and the ones that do point at something the record can answer.
Build the claim from the clinical note
Pabau keeps clinical notes, imaging and invoices on one patient record, and routes claims through the Claim.MD integration for review before submission. Book a demo to see it on your own sequela claims.
Conclusion
The hard part of S59.221S is rarely the code itself. It is proving, on the claim, that today’s deformity or growth arrest traces back to a fracture treated years earlier.
Practices that check sequencing and laterality before transmission recover more on first pass than those that appeal afterwards. The work is the same either way, but it costs less when it happens before the claim leaves.
Pabau keeps the clinical note, the imaging report and the claim on one patient record, so those checks happen where the evidence already is. Book a demo to see how Pabau supports sequela coding in your practice.
Continue your research
Managing claim denials across your practice? Submitting a clean claim walks through the fields and documentation standards that prevent most first-pass rejections.
Need a deeper look at the clearinghouse process? How Claim.MD clearinghouse works explains how 837P validation and ERA processing reduce manual claim follow-up for US practices.
Billing for physical therapy sequela visits? Medical billing fundamentals covers documentation standards that apply across CPT code pairings for rehabilitation encounters.
Frequently asked questions
What does ICD-10 Code S59.221S mean?
ICD-10 Code S59.221S is the billable diagnosis code for sequela of a Salter-Harris Type II physeal fracture of the right distal radius physis. It applies when a patient presents with a residual condition caused by a prior growth plate fracture at the wrist. The original injury must have finished healing. The residual condition code is sequenced first; S59.221S follows as the causal explanation.
What is the difference between S59.221A and S59.221S?
S59.221A (seventh character A) is used at the initial encounter when the patient is receiving active treatment for the acute Salter-Harris Type II fracture. S59.221S (seventh character S) is used only after healing is complete. The visit is then for a residual condition left by that fracture, such as growth arrest or angular deformity. Using “A” once the acute phase has ended is a coding error that payers typically deny.
Can S59.221S be used for adult patients?
Yes. S59.221S is not restricted to pediatric patients. Take an adult who broke the distal radius physis as a child and now presents with angular deformity. S59.221S is the correct causal code, whatever the current age. The physis no longer exists in a skeletally mature adult, but the sequela of the prior physeal fracture remains a valid diagnosis.
When should you use the seventh character S in ICD-10-CM fracture coding?
Use the seventh character S when the current encounter is for a condition caused by a prior fracture. The fracture itself must no longer be in an active healing phase. The residual condition (stiffness, deformity, growth disturbance) is what prompted the visit; the “S” code explains why that condition exists. If any active fracture treatment is still ongoing, use “D” instead.
What are the most common reasons payers deny claims coded with S59.221S?
Four reasons account for most denials. The first is incorrect sequencing, where S59.221S is listed as the primary diagnosis rather than the residual condition code. The second is using character A or D after the healing phase has ended. The third is no documented history of the original Salter-Harris Type II fracture. The fourth is a laterality mismatch between the code submitted and the side documented in the note.
Which CPT codes are most commonly paired with S59.221S?
Common CPT pairings include E&M visit codes 99213-99215 for follow-up evaluations and CPT 25350 for distal-third radius osteotomy when malunion is corrected surgically. Physical therapy evaluation codes 97161-97163 and wrist X-ray codes 73100 and 73110 also pair with this diagnosis. Payer acceptance of each pairing varies, so verify coverage before the procedure.