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HCPCS Code

HCPCS code Q4167 – Truskin skin substitute, per square centimeter


Code Definition

Q4167 is the HCPCS Level II code for Truskin, per square centimeter (add-on, list separately in addition to primary procedure). It covers the skin substitute itself, while a CPT application code from 15271-15278 covers the work of placing it.

Units matter most. One unit equals one square centimeter of Truskin applied, so the chart, the invoice and the claim must agree. Because skin substitutes are high-cost items, a small counting error can become a large refund request. Get the units, the CPT pairing and prior authorization right, and the claim has little left to trip on.

Code range
Q0035-Q9999 Temporary Codes
Category
Q — Temporary codes
Code range
Q4101-Q4440 Skin Substitutes and Biologicals
Billable
No
Code also known as
wound matrix, cellular tissue-based product, CTP, skin and soft tissue substitute
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Key takeaways

Key takeaways

HCPCS code Q4167 bills Truskin skin substitute per square centimeter, separately from the CPT code for applying it.

Wound site and total wound area decide the application code, and foot and toe wounds bill under 15275-15278.

Most Medicare Advantage and commercial plans want prior authorization on file before the product is applied.

Units must match the square centimeters in the chart and the lot number on the delivery invoice.

Vague diagnosis codes and missing standard-care notes cause many preventable Q4167 denials.

HCPCS code Q4167 bills Truskin one square centimeter at a time

HCPCS code Q4167 is a temporary Level II Q-code for Truskin, a skin substitute used on chronic wounds. You bill one unit for each square centimeter applied. The work of applying it goes on the same claim under a separate CPT code.

The Centers for Medicare and Medicaid Services (CMS) issues Q-codes for products that don’t yet have a permanent code. It updates them every quarter, and a Q-code can be revised or retired along the way. Q4167 sits in the Q4101-Q4440 group of skin substitutes and biologicals, where each code belongs to one product.

Field Detail
Code Q4167
Product Truskin
Code set HCPCS Level II (temporary Q-code)
Product type Skin substitute / cellular and tissue-based product (CTP)
Primary indications Diabetic foot ulcer (DFU), venous leg ulcer (VLU)
Billing unit One unit per square centimeter of Truskin applied
Maintained by CMS (Centers for Medicare and Medicaid Services)
Coverage governed by Medicare Administrative Contractor (MAC) local coverage determinations (LCDs)
Care settings Hospital outpatient (OPPS), physician office

Before you bill, check the descriptor against the latest CMS quarterly HCPCS file. Skin substitute descriptors do change, and billing against an old one can get the claim denied.

Q4167 coverage starts with a wound that failed standard care

Q4167 is covered for chronic wounds that haven’t healed with standard wound care and that meet your MAC’s local coverage determination. Coverage isn’t automatic, though. The chart has to show the wound qualifies before the claim goes out.

Wound types payers usually cover

  • Diabetic foot ulcers (DFU): full-thickness neuropathic ulcers on the plantar surface or distal foot in patients with documented diabetes
  • Venous leg ulcers (VLU): chronic venous stasis ulcers that haven’t responded to standard compression therapy, typically for four weeks or more
  • Pressure ulcers: covered under some MAC LCDs once standard care has been exhausted, so check the specific LCD first

Uses that won’t be covered

  • Acute surgical wounds and traumatic lacerations
  • Burns where a different product-specific Q-code applies
  • Wound types the applicable LCD doesn’t list
  • Wounds that haven’t had the required stretch of standard wound care before the skin substitute

What if the clinical team wants Q4167 for a wound the LCD doesn’t list? Write down the clinical reasoning in detail. Then check coverage with the payer before the product goes on, because off-label use invites both denials and audits.

Q4167 units come from the chart, not the box

Bill one unit of Q4167 for each square centimeter of Truskin applied. The unit count has to line up with the wound measurements in the note and the product on the invoice.

Here’s how a typical Q4167 claim moves from the treatment room to the payer:

  1. The clinician measures the wound (length x width in cm) and records it in the note.
  2. The note captures the product name, lot number and square centimeters applied.
  3. The biller turns those square centimeters into Q4167 units and picks the CPT application code.
  4. Diagnosis codes, place of service and any prior authorization number go on the claim.
  5. The payer checks the billed units against the documented wound size.
Billing element Guidance
Unit calculation One unit per square centimeter of Truskin applied. Base it on the documented wound measurements and the product used. Bill discarded product only where the payer’s wastage policy allows it.
Place of service: facility Hospital outpatient (POS 22): the facility bills the product, and the application is billed with CPT 15271-15278.
Place of service: non-facility Physician office (POS 11): the practice bills both Q4167 and the CPT application code.
Common modifiers RT/LT for laterality, and modifier 59 or XS for multiple wounds on the same date. Confirm modifier rules with your MAC.
OPPS classification Q4167 may be packaged or separately payable under OPPS. Check the payment indicator in the current OPPS Addendum B.

Auditors compare the documented wound size with the units on the claim. So record the measurements on the date of service, and tie the lot number to the units billed.

Wound site and size pick the CPT code that rides with Q4167

Choose the application code by where the wound is and how large the total wound area is. Q4167 only covers the product, so the claim also needs one of CPT codes 15271-15278. Leave the application code off and the claim comes back incomplete.

CPT code Description When to use with Q4167
15271 Skin substitute application, trunk/arms/legs, total wound area up to 100 sq cm, first 25 sq cm or less VLU on the lower leg, first 25 sq cm
15272 Each additional 25 sq cm, or part thereof (add-on to 15271) Each extra 25 sq cm on the same site group
15273 Trunk/arms/legs, total wound area 100 sq cm or more, first 100 sq cm Large lower-leg ulcers
15274 Each additional 100 sq cm, or part thereof (add-on to 15273) Each extra 100 sq cm on a large trunk, arm or leg wound
15275 Face/scalp/eyelids/mouth/neck/ears/orbits/genitalia/hands/feet/multiple digits, total wound area up to 100 sq cm, first 25 sq cm or less DFU on the toes or plantar foot
15276 Each additional 25 sq cm, or part thereof (add-on to 15275) Each extra 25 sq cm on foot and toe sites
15277 Same sites as 15275, total wound area 100 sq cm or more, first 100 sq cm Large foot wounds
15278 Each additional 100 sq cm, or part thereof (add-on to 15277) Each extra 100 sq cm on those sites

The grid below puts those eight codes side by side, with a worked foot ulcer example.

Grid of skin substitute application codes billed with Q4167
Site sets the row and total wound area sets the column, while Q4167 units follow the square centimeters applied. Code ranges follow the AMA CPT and CMS HCPCS descriptors.

Take a 40 sq cm diabetic ulcer on the plantar foot, covered with 40 sq cm of Truskin. The claim carries 15275 for the first 25 sq cm and one unit of 15276 for the remaining 15. Q4167 then goes on as 40 units.

Mismatching the site and the CPT pair is an easy audit trigger. Lower-leg VLUs belong under 15271-15274, while foot and toe DFUs belong under 15275-15278. Our 15271 guide covers the application side in more depth.

Diagnosis codes have to prove medical necessity for Q4167

Every Q4167 claim needs an ICD-10-CM code that satisfies the MAC’s LCD. It should describe both the wound and the condition behind it. Vague diagnosis codes are a common reason these claims get denied.

ICD-10-CM code Description Notes
E11.621 Type 2 diabetes with foot ulcer Most common primary DFU diagnosis. Pair it with L97.4xx or L97.5xx for wound location.
E10.621 Type 1 diabetes with foot ulcer Use when type 1 diabetes is documented. Same pairing rules as E11.621.
L97.419 Non-pressure chronic ulcer of right heel and midfoot with unspecified severity Secondary code for wound location. Choose the most specific severity code available.
I87.2 Venous insufficiency (chronic) (peripheral) Primary diagnosis for VLU claims. Pair it with L97.2xx or L97.3xx for lower-leg wound location.
L97.209 Non-pressure chronic ulcer of unspecified calf with unspecified severity Secondary wound location code for VLU. Code laterality and severity to the highest documented level.

Code to the most specific level the note supports. An unspecified severity code only fits when the chart doesn’t record wound depth. If the note describes full-thickness tissue loss, the claim should say so as well.

Neighboring Q-codes look alike but bill different products

Q4167 covers a single product, Truskin. The codes on either side of it belong to other manufacturers’ products, so they can’t be swapped in. Bill the wrong one and you get a product-mismatch denial that’s hard to appeal without proof of what was applied.

Code Product / category Key distinction from Q4167
Q4166 Adjacent product-specific skin substitute Different manufacturer’s product. It can’t be substituted, even for an identical wound.
Q4167 Truskin Bill only when Truskin was applied. Check the product against the CMS quarterly HCPCS update.
Q4168 Adjacent product-specific skin substitute Different manufacturer’s product. The lot number and invoice must match the billed code.
Q4169 Adjacent product-specific skin substitute Different manufacturer’s product. Using it for Truskin is a billing error.

Match the Q-code to the product using the current CMS quarterly HCPCS file, or confirm it in the AAPC Codify HCPCS lookup. When a product moves to a new Q-code, billing the old one earns a retired-code denial.

Prior authorization decides whether a Q4167 claim gets paid

Traditional Medicare doesn’t require formal prior authorization for Q4167, but most Medicare Advantage and commercial plans do. Skin substitutes are high-cost products, so these plans add their own approval step on top of the LCD criteria. A pass under the MAC’s rules doesn’t guarantee approval from a Medicare Advantage plan.

Payer type Prior authorization Coverage notes
Traditional Medicare (Part B) No formal PA, but LCD criteria must be documented Coverage follows the applicable MAC LCD. Noridian, Novitas, CGS and Palmetto GBA LCDs vary by jurisdiction.
Medicare Advantage (e.g. Highmark MA) Required in most plans Plans treat the LCD as a floor and may add criteria. Check each plan’s PA list every plan year.
UnitedHealthcare / Oxford Required Skin substitute Q-codes appear on UHC’s PA list. Send wound measurements and prior treatment history.
Molina Healthcare Required (Policy 357 referenced) Explicit DFU and VLU criteria. Requests without documented standard-care failure are usually denied.
Fidelis Care Required LCD-based criteria apply. Verify the active policy before each application episode.
Medicaid managed care Varies by state plan Some state programs don’t cover skin substitute Q-codes. Confirm coverage before ordering product.

Keep a running list of which patients hold active authorization for Q4167 and when each approval expires. Product applied after approval lapses, or beyond the approved units, leads to a non-covered-charge denial. For Medicare beneficiaries, that charge can’t simply be passed on to the patient.

Medicare reimbursement for Q4167 follows the CMS update cycle

Medicare sets Q4167 payment through the OPPS Addendum B and the Physician Fee Schedule (PFS). OPPS rates update quarterly and the PFS updates yearly. Because the rate moves, this guide doesn’t quote a fixed dollar amount.

Instead, look up the current figure in the CMS Physician Fee Schedule search tool, or download the latest OPPS Addendum B file. In facility settings, the OPPS payment indicator shows whether Q4167 is paid separately or packaged into the APC payment.

Most Q4167 denials trace back to six fixable causes

The good news is that most Q4167 denials are preventable. A high-cost product, strict LCD criteria and frequent prior authorization rules mean small misses get caught. The table pairs each common cause with its fix.

Denial reason Root cause Resolution
Missing prior authorization Product applied without PA on file for a payer that requires it Get PA before each treatment episode and track expiry dates. Never apply product without a confirmed PA number.
Non-covered indication Wound type isn’t in the MAC LCD or payer policy Review the LCD before ordering product. Document that the wound meets each listed criterion.
Incorrect units Billed units exceed what the documented wound measurements support Record wound length, width and depth on the date of service. Confirm the units match the product applied.
Insufficient standard care documentation The LCD requires four or more weeks of standard care, and the chart doesn’t show it Include dated wound care notes covering the full pre-treatment period. A single note isn’t enough.
Wrong or unspecified diagnosis code The ICD-10 code isn’t on the LCD’s covered diagnosis list Code to the highest documented specificity. Check the code against the MAC LCD before submitting.
Wrong Q-code submitted A neighboring Q-code was used instead of Q4167 Match the Q-code to the lot number on the delivery invoice. Keep product records for each application.

When a denial does arrive, the remittance code tells you which of these causes you’re facing. Our guide to decoding denial codes maps each one to its next step.

Pro Tip

Before each Q4167 application, capture three details in the note: wound measurements in centimeters, the product lot number and an active prior authorization number. Recording them at the point of care is far easier than rebuilding them after a denial.

Before you submit: a Q4167 documentation checklist

Run through this list before a Q4167 claim leaves the practice. Each item is one that reviewers often find missing on denied skin substitute claims.

  • Patient diagnosis: active ICD-10-CM codes for the underlying condition (diabetes type, venous insufficiency) and the wound location and severity
  • Wound assessment: wound measurements (length x width in cm) recorded on the date Q4167 was applied
  • Standard care history: dated wound care notes covering the pre-treatment period the LCD requires, typically four weeks or more
  • Product documentation: product name, lot number and quantity applied, cross-checked with the supplier invoice
  • Prior authorization: PA number, authorizing payer, approval date and expiry date on file before application
  • Wound bed preparation note: a short description of the wound bed and how it was prepared
  • Ordering provider eligibility: confirmation that the provider can order Q4167 under state and payer rules
  • Consent: patient consent for the procedure, where the facility or payer requires it
  • Unit calculation worksheet: an internal note showing how the billed units were worked out

If an item is missing, fix it before the claim goes out. Rebuilding a record after a denial takes far longer than completing it on the day.

How claims software keeps Q4167 claims complete before they go out

In many wound care practices, the biller builds each Q4167 claim by hand. Measurements come from the note, units from the invoice and the authorization number from an email. Every hand-off is another chance for those numbers to drift apart.

Pabau, the practice management platform we build, offers cleaner claims management by starting from the patient record. The code attached to the service lands on the charge line, and diagnosis codes come from the patient’s problem list. A HCPCS, CPT and ICD-10 lookup library sits beside each field.

The claim won’t send until required fields, such as the authorization number, are filled in. In the US, claims go out through Claim.MD, with eligibility checks and remittance posting built in. As a result, your biller spends less time chasing numbers, and fewer claims bounce for missing details.

Pabau checkout screen with a completed invoice billed to an insurer
Pabau closes checkout and raises the insurer invoice in one step, so the skin substitute charge is ready to claim when the visit ends.

Send complete skin substitute claims with Pabau

Pabau pre-fills each claim from the patient record and holds it until required fields like the authorization number are complete. That means fewer wound care claims come back for missing details.

Pabau claims management dashboard

Conclusion

A Q4167 claim is won or lost before anyone opens the billing screen. When the measurements, the lot number and the authorization are in the chart on the day of service, the claim is simple to build. When they’re missing, even a skilled coder can’t rebuild them later.

So make those three details a habit at the point of care, and audit a handful of claims each month against your MAC’s LCD. It costs a minute or two per visit, which is far less than working through refund requests and appeals.

Book a demo to see how Pabau carries skin substitute claims from the treatment note to the payer with every required field in place.

Continue your research

Continue your research

Dealing with repeat skin substitute denials? Denial management in healthcare sets out a workflow for investigating, appealing and preventing claim rejections.

Want the application side of the claim? CPT code 15271 explains how skin substitute graft application is billed on the trunk, arms and legs.

Billing another skin substitute? HCPCS code Q4127 walks through Talymed units, application codes and payment.

Need a refresher on the revenue cycle? What is medical billing? explains how a claim moves from visit to payment in US practices.

Worried about audit exposure? Medical billing compliance covers the rules and habits that keep claims audit-ready.

Frequently asked questions

Is Q4167 billed on a CMS-1500 or a UB-04?

It depends on who bills the product. A physician office reports Q4167 on the CMS-1500 (or its 837P electronic version). A hospital outpatient department reports it on the UB-04 (837I), alongside its revenue codes.

Can a practice bill the patient if Medicare denies Q4167?

Only if the patient signed a valid Advance Beneficiary Notice of Noncoverage (ABN) before the product was applied. Without an ABN, a medical-necessity denial generally can’t be shifted to the Medicare patient. Record the ABN with the GA modifier on the claim.

Can a nurse practitioner bill Q4167?

Yes, where state scope-of-practice rules and the payer allow nurse practitioners to apply skin substitutes. The NP reports the claim under their own NPI. Medicare generally pays the application code at 85% of the physician fee schedule rate.

Does each new wound need its own prior authorization?

Usually, yes. Most payers tie an approval to a specific wound, product, unit count and date range. A new wound, a switch in product or extra applications normally means a new or amended request.

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