{"id":177318,"date":"2026-08-13T11:00:50","date_gmt":"2026-08-13T11:00:50","guid":{"rendered":"https:\/\/pabau.com\/?p=177318"},"modified":"2026-08-13T12:26:15","modified_gmt":"2026-08-13T12:26:15","slug":"hcpcs-code-j1441","status":"publish","type":"post","link":"https:\/\/pabau.com\/nl\/procedure-codes\/hcpcs-code-j1441\/","title":{"rendered":"HCPCS code J1441: Filgrastim (G-CSF) 480 mcg injection guide"},"content":{"rendered":"\n<script type=\"application\/ld+json\">{\"@context\":\"https:\/\/schema.org\",\"@type\":\"MedicalWebPage\",\"headline\":\"HCPCS Code J1441: Filgrastim (G-CSF) 480 mcg - Deleted Code Reference\",\"description\":\"HCPCS code J1441 (Injection, filgrastim\/G-CSF, 480 mcg) was deleted effective January 1, 2014. See the crosswalk to J1442, the biosimilar codes, and how to bill filgrastim today.\",\"url\":\"https:\/\/pabau.com\/procedure-codes\/hcpcs-code-j1441\/\",\"audience\":{\"@type\":\"MedicalAudience\",\"audienceType\":\"Clinician\"},\"reviewedBy\":{\"@type\":\"Person\",\"name\":\"Dr Vanja Kitanova\",\"jobTitle\":\"Medical Reviewer\",\"affiliation\":{\"@type\":\"Organization\",\"name\":\"Pabau\"},\"knowsAbout\":[\"Medical Coding\",\"Clinical Documentation\",\"Healthcare Billing\",\"Clinical Safety\"],\"sameAs\":\"https:\/\/pabau.com\/blog\/author\/vanja\/\"},\"datePublished\":\"2026-08-07\",\"dateModified\":\"2026-08-13\"}<\/script>\n\n\n        <div id=\"key_takeaways\">\n            <div class=\"header\">\n                                    <img decoding=\"async\" src=\"https:\/\/pabau.com\/wp-content\/uploads\/2025\/12\/Key-Takeaways-Icon.svg\" alt=\"Key takeaways\" height=\"42\" width=\"42\">\n                                <h3>Key takeaways<\/h3>\n            <\/div>\n            <div class=\"list\">\n                                                            <div class=\"item\">\n                            <div>\n                                <svg width=\"20\" height=\"27\" viewBox=\"0 0 20 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\n                                    <path\n                                        d=\"M18.6223 14.3857C19.1246 13.8975 19.1246 13.1045 18.6223 12.6162L12.1938 6.36621C11.6915 5.87793 10.8759 5.87793 10.3737 6.36621C9.87143 6.85449 9.87143 7.64746 10.3737 8.13574L14.6125 12.2529H2.28571C1.57455 12.2529 1 12.8115 1 13.5029C1 14.1943 1.57455 14.7529 2.28571 14.7529H14.6085L10.3777 18.8701C9.87545 19.3584 9.87545 20.1514 10.3777 20.6396C10.8799 21.1279 11.6955 21.1279 12.1978 20.6396L18.6263 14.3896L18.6223 14.3857Z\"\n                                        fill=\"#3D3D46\" \/>\n                                <\/svg>\n                            <\/div>\n                            <p>HCPCS code J1441 described a flat 480 mcg dose of filgrastim (G-CSF) and is no longer in the active HCPCS Level II code set.<\/p>\n                        <\/div>\n                                                                                <div class=\"item\">\n                            <div>\n                                <svg width=\"20\" height=\"27\" viewBox=\"0 0 20 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\n                                    <path\n                                        d=\"M18.6223 14.3857C19.1246 13.8975 19.1246 13.1045 18.6223 12.6162L12.1938 6.36621C11.6915 5.87793 10.8759 5.87793 10.3737 6.36621C9.87143 6.85449 9.87143 7.64746 10.3737 8.13574L14.6125 12.2529H2.28571C1.57455 12.2529 1 12.8115 1 13.5029C1 14.1943 1.57455 14.7529 2.28571 14.7529H14.6085L10.3777 18.8701C9.87545 19.3584 9.87545 20.1514 10.3777 20.6396C10.8799 21.1279 11.6955 21.1279 12.1978 20.6396L18.6263 14.3896L18.6223 14.3857Z\"\n                                        fill=\"#3D3D46\" \/>\n                                <\/svg>\n                            <\/div>\n                            <p>CMS deleted J1441 effective January 1, 2014, so December 31, 2013 was the last valid date of service for the code.<\/p>\n                        <\/div>\n                                                                                <div class=\"item\">\n                            <div>\n                                <svg width=\"20\" height=\"27\" viewBox=\"0 0 20 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\n                                    <path\n                                        d=\"M18.6223 14.3857C19.1246 13.8975 19.1246 13.1045 18.6223 12.6162L12.1938 6.36621C11.6915 5.87793 10.8759 5.87793 10.3737 6.36621C9.87143 6.85449 9.87143 7.64746 10.3737 8.13574L14.6125 12.2529H2.28571C1.57455 12.2529 1 12.8115 1 13.5029C1 14.1943 1.57455 14.7529 2.28571 14.7529H14.6085L10.3777 18.8701C9.87545 19.3584 9.87545 20.1514 10.3777 20.6396C10.8799 21.1279 11.6955 21.1279 12.1978 20.6396L18.6263 14.3896L18.6223 14.3857Z\"\n                                        fill=\"#3D3D46\" \/>\n                                <\/svg>\n                            <\/div>\n                            <p>J1442 (filgrastim, excludes biosimilars, 1 microgram) is the active replacement, billed as 480 units for a 480 mcg dose.<\/p>\n                        <\/div>\n                                                                                <div class=\"item\">\n                            <div>\n                                <svg width=\"20\" height=\"27\" viewBox=\"0 0 20 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\n                                    <path\n                                        d=\"M18.6223 14.3857C19.1246 13.8975 19.1246 13.1045 18.6223 12.6162L12.1938 6.36621C11.6915 5.87793 10.8759 5.87793 10.3737 6.36621C9.87143 6.85449 9.87143 7.64746 10.3737 8.13574L14.6125 12.2529H2.28571C1.57455 12.2529 1 12.8115 1 13.5029C1 14.1943 1.57455 14.7529 2.28571 14.7529H14.6085L10.3777 18.8701C9.87545 19.3584 9.87545 20.1514 10.3777 20.6396C10.8799 21.1279 11.6955 21.1279 12.1978 20.6396L18.6263 14.3896L18.6223 14.3857Z\"\n                                        fill=\"#3D3D46\" \/>\n                                <\/svg>\n                            <\/div>\n                            <p>J1440 is not the replacement. It was deleted in the same 2014 action, and CMS reassigned the number to Rebyota.<\/p>\n                        <\/div>\n                                                                                <div class=\"item\">\n                            <div>\n                                <svg width=\"20\" height=\"27\" viewBox=\"0 0 20 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\n                                    <path\n                                        d=\"M18.6223 14.3857C19.1246 13.8975 19.1246 13.1045 18.6223 12.6162L12.1938 6.36621C11.6915 5.87793 10.8759 5.87793 10.3737 6.36621C9.87143 6.85449 9.87143 7.64746 10.3737 8.13574L14.6125 12.2529H2.28571C1.57455 12.2529 1 12.8115 1 13.5029C1 14.1943 1.57455 14.7529 2.28571 14.7529H14.6085L10.3777 18.8701C9.87545 19.3584 9.87545 20.1514 10.3777 20.6396C10.8799 21.1279 11.6955 21.1279 12.1978 20.6396L18.6263 14.3896L18.6223 14.3857Z\"\n                                        fill=\"#3D3D46\" \/>\n                                <\/svg>\n                            <\/div>\n                            <p>Biosimilar filgrastim carries product-specific codes, including Q5101 for Zarxio and Q5110 for Nivestym. J3262 is tocilizumab, not filgrastim.<\/p>\n                        <\/div>\n                                                                                <div class=\"item\">\n                            <div>\n                                <svg width=\"20\" height=\"27\" viewBox=\"0 0 20 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\n                                    <path\n                                        d=\"M18.6223 14.3857C19.1246 13.8975 19.1246 13.1045 18.6223 12.6162L12.1938 6.36621C11.6915 5.87793 10.8759 5.87793 10.3737 6.36621C9.87143 6.85449 9.87143 7.64746 10.3737 8.13574L14.6125 12.2529H2.28571C1.57455 12.2529 1 12.8115 1 13.5029C1 14.1943 1.57455 14.7529 2.28571 14.7529H14.6085L10.3777 18.8701C9.87545 19.3584 9.87545 20.1514 10.3777 20.6396C10.8799 21.1279 11.6955 21.1279 12.1978 20.6396L18.6263 14.3896L18.6223 14.3857Z\"\n                                        fill=\"#3D3D46\" \/>\n                                <\/svg>\n                            <\/div>\n                            <p>Practice management software like Pabau flags retired codes before submission and keeps drug administration records attached to the claim.<\/p>\n                        <\/div>\n                                                <\/div>\n        <\/div>\n    \n\n\n<p class=\"wp-block-paragraph\">HCPCS code J1441 described an injection of filgrastim (granulocyte colony-stimulating factor, G-CSF) at a flat dose of 480 mcg. Filgrastim stimulates neutrophil production in patients receiving chemotherapy, undergoing bone marrow transplant, or living with severe chronic neutropenia. Neupogen (Amgen) was the originator brand billed under this code.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The code is no longer valid. CMS deleted J1441 effective January 1, 2014, in the annual HCPCS Level II update. Its sister flat-dose code J1440 (300 mcg) was retired in the same action, and one per-microgram code, J1442, replaced both.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The old J1440 number is in use again, but CMS reassigned it to an unrelated product, Rebyota (fecal microbiota, live-jslm). A filgrastim claim submitted under J1440 today reports the wrong drug. Anything still billed under J1441 fails at the clearinghouse before a payer ever sees it.<\/p>\n\n\n\n<h2 id=\"h-j1441-code-details-at-a-glance\" class=\"wp-block-heading\">J1441 code details at a glance<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The table below lists the reference data for HCPCS code J1441 (Injection, filgrastim (G-CSF), 480 mcg). It is what you need when auditing historical claims or answering a payer query about a pre-2014 encounter. For current billing, use the crosswalk in the next section.<\/p>\n\n\n\n<table style=\"width:100%;border-collapse:separate;border-spacing:0;border-radius:12px;overflow:hidden;font-size:15px;line-height:1.5;margin:1.5em 0 2em;box-shadow:0 2px 12px rgba(0,0,0,0.08)\">\n<thead>\n<tr>\n<th style=\"background:#121D36;color:#fff;padding:14px 16px;text-align:left;font-weight:600;font-size:14px;letter-spacing:0.3px;border-bottom:2px solid #2BADD4\">Field<\/th>\n<th style=\"background:#121D36;color:#fff;padding:14px 16px;text-align:left;font-weight:600;font-size:14px;letter-spacing:0.3px;border-bottom:2px solid #2BADD4\">Value<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr style=\"border-bottom:1px solid #E8ECF0\">\n<td style=\"padding:12px 16px;font-weight:600;color:#121D36\">HCPCS code<\/td>\n<td style=\"padding:12px 16px;color:#374151\">J1441<\/td>\n<\/tr>\n<tr style=\"border-bottom:1px solid #E8ECF0;background:#F9FAFB\">\n<td style=\"padding:12px 16px;font-weight:600;color:#121D36\">Official descriptor<\/td>\n<td style=\"padding:12px 16px;color:#374151\">Injection, filgrastim (G-CSF), 480 mcg<\/td>\n<\/tr>\n<tr style=\"border-bottom:1px solid #E8ECF0\">\n<td style=\"padding:12px 16px;font-weight:600;color:#121D36\">Code status<\/td>\n<td style=\"padding:12px 16px;color:#374151\">Deleted (inactive)<\/td>\n<\/tr>\n<tr style=\"border-bottom:1px solid #E8ECF0;background:#F9FAFB\">\n<td style=\"padding:12px 16px;font-weight:600;color:#121D36\">Code type<\/td>\n<td style=\"padding:12px 16px;color:#374151\">HCPCS Level II, J-code (injectable drug)<\/td>\n<\/tr>\n<tr style=\"border-bottom:1px solid #E8ECF0\">\n<td style=\"padding:12px 16px;font-weight:600;color:#121D36\">Billing unit<\/td>\n<td style=\"padding:12px 16px;color:#374151\">Per 480 mcg dose (flat dose)<\/td>\n<\/tr>\n<tr style=\"border-bottom:1px solid #E8ECF0;background:#F9FAFB\">\n<td style=\"padding:12px 16px;font-weight:600;color:#121D36\">Drug class<\/td>\n<td style=\"padding:12px 16px;color:#374151\">Granulocyte colony-stimulating factor (G-CSF)<\/td>\n<\/tr>\n<tr style=\"border-bottom:1px solid #E8ECF0\">\n<td style=\"padding:12px 16px;font-weight:600;color:#121D36\">Brand name (originator)<\/td>\n<td style=\"padding:12px 16px;color:#374151\">Neupogen (Amgen)<\/td>\n<\/tr>\n<tr style=\"border-bottom:1px solid #E8ECF0;background:#F9FAFB\">\n<td style=\"padding:12px 16px;font-weight:600;color:#121D36\">Last valid date of service<\/td>\n<td style=\"padding:12px 16px;color:#374151\">December 31, 2013<\/td>\n<\/tr>\n<tr style=\"border-bottom:1px solid #E8ECF0\">\n<td style=\"padding:12px 16px;font-weight:600;color:#121D36\">Deletion date<\/td>\n<td style=\"padding:12px 16px;color:#374151\">January 1, 2014 (annual HCPCS update)<\/td>\n<\/tr>\n<tr style=\"border-bottom:1px solid #E8ECF0;background:#F9FAFB\">\n<td style=\"padding:12px 16px;font-weight:600;color:#121D36\">Primary replacement<\/td>\n<td style=\"padding:12px 16px;color:#374151\">J1442 (filgrastim, excludes biosimilars, 1 microgram)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n\n<h2 id=\"h-is-j1441-still-active-code-status-and-deletion-history\" class=\"wp-block-heading\">Is J1441 still active? Code status and deletion history<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">HCPCS code J1441 is not active. CMS deleted it effective January 1, 2014, in the annual HCPCS Level II update announced in late 2013. December 31, 2013 was the last date of service the code could cover.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The change was about billing units rather than coverage. Both flat-dose filgrastim codes went at once, J1440 for 300 mcg and J1441 for 480 mcg. CMS replaced them with J1442, which bills per 1 microgram, so the claim carries the dose given instead of a vial size.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A second deletion date circulates online. Several billing write-ups place the removal of J1441 in a mid-year 2019 HCPCS update. No mid-year 2019 update touched this code. The only CMS document that names J1440 and J1441 together is program memorandum A02050, published in 2002 while both codes were still active.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">If J1441 still sits in your charge master, filgrastim claims will not reach adjudication. Clearinghouses reject codes that are absent from the active CMS HCPCS file, so the claim never becomes a payer denial. It never enters the denial queue either, which is how a retired code keeps failing quietly for months.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Revenue cycle teams should re-audit the charge master at every quarterly HCPCS update. That catches deletions before they reach a claim, and it catches reassigned numbers like J1440 before they reach the wrong drug.<\/p>\n\n\n        <div id=\"pro_tip\">\n            <div class=\"img\">\n                <svg width=\"42\" height=\"42\" viewBox=\"0 0 42 42\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\n                    <path fill-rule=\"evenodd\" clip-rule=\"evenodd\"\n                        d=\"M12.6383 19.5238C12.6632 21.2071 12.8734 22.9926 12.0685 24.5523C11.0341 26.8917 8.45076 28.169 7.56292 30.5918C6.63082 33.1061 7.19505 36.185 9.31371 37.9786C10.929 39.5678 13.4183 39.9873 15.6061 39.5463C17.4592 39.073 19.1049 37.8388 19.9706 36.1608C20.781 34.7141 20.7866 32.9904 20.5293 31.3985C20.1006 29.3092 18.3775 27.8705 16.9807 26.362C14.8814 24.1005 14.6684 20.6854 15.595 17.8915C16.4331 15.4768 19.0026 14.2344 20.0425 11.9461C20.7202 10.6769 20.7506 9.20327 20.6068 7.81304C20.1864 5.40098 18.3139 3.23631 15.8716 2.56674C13.9742 2.03969 11.8224 2.30052 10.1739 3.37614C8.70522 4.34688 7.5878 5.86618 7.28356 7.58178C6.76081 9.82981 7.53525 12.2822 9.20307 13.9118C10.7658 15.4741 12.4806 17.2273 12.6383 19.5238Z\"\n                        fill=\"#2BADD4\" \/>\n                    <path fill-rule=\"evenodd\" clip-rule=\"evenodd\"\n                        d=\"M22.7048 19.8387C22.6822 22.3279 24.4507 24.6234 26.7493 25.4682C28.0531 25.961 29.4725 25.9183 30.7989 25.5487C32.0575 24.9955 33.301 24.2237 34.0069 23.0092C34.8384 21.5811 35.2982 19.8286 34.7832 18.2094C34.3611 16.2507 32.8739 14.6541 31.0275 13.9426C28.6736 12.9595 25.8073 13.7942 24.1719 15.7001C23.2022 16.8366 22.6143 18.3326 22.7048 19.8387Z\"\n                        fill=\"#2BADD4\" \/>\n                <\/svg>\n            <\/div>\n            <div class=\"text\">\n                <h3>Pro Tip<\/h3>\n                <p>Audit your charge master against the CMS HCPCS quarterly update files every January, April, July, and October. Deleted codes drop silently from the active code list, and most systems do not flag legacy codes unless a validation rule is configured. A one-hour quarterly audit prevents months of unnoticed rejections.<\/p>\n            <\/div>\n        <\/div>\n    \n\n\n<h2 id=\"h-what-code-replaced-j1441-crosswalk-to-active-codes\" class=\"wp-block-heading\">What code replaced J1441? Crosswalk to active codes<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">J1442 replaced HCPCS code J1441. Its descriptor is injection, filgrastim (G-CSF), excludes biosimilars, 1 microgram, so the quantity field carries the micrograms given. A 480 mcg Neupogen dose is billed as J1442 with 480 units.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Do not reach for J1440 as the replacement. That code was deleted alongside J1441 in 2014, and CMS has since reassigned the number to Rebyota (fecal microbiota, live-jslm, 1 ml). A filgrastim claim submitted under J1440 now reports a Clostridioides difficile therapy instead.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The table below maps J1441 to the codes in use today. Verify each entry against the <a href=\"https:\/\/www.cms.gov\/medicare\/coding-billing\/healthcare-common-procedure-system\" target=\"_blank\" rel=\"nofollow noopener\">CMS HCPCS overview<\/a> and the current annual code file before a billing cycle.<\/p>\n\n\n\n<table style=\"width:100%;border-collapse:separate;border-spacing:0;border-radius:12px;overflow:hidden;font-size:15px;line-height:1.5;margin:1.5em 0 2em;box-shadow:0 2px 12px rgba(0,0,0,0.08)\">\n<thead>\n<tr>\n<th style=\"background:#121D36;color:#fff;padding:14px 16px;text-align:left;font-weight:600;font-size:14px;letter-spacing:0.3px;border-bottom:2px solid #2BADD4\">Code<\/th>\n<th style=\"background:#121D36;color:#fff;padding:14px 16px;text-align:left;font-weight:600;font-size:14px;letter-spacing:0.3px;border-bottom:2px solid #2BADD4\">Descriptor<\/th>\n<th style=\"background:#121D36;color:#fff;padding:14px 16px;text-align:left;font-weight:600;font-size:14px;letter-spacing:0.3px;border-bottom:2px solid #2BADD4\">Drug \/ brand<\/th>\n<th style=\"background:#121D36;color:#fff;padding:14px 16px;text-align:left;font-weight:600;font-size:14px;letter-spacing:0.3px;border-bottom:2px solid #2BADD4\">Status<\/th>\n<th style=\"background:#121D36;color:#fff;padding:14px 16px;text-align:left;font-weight:600;font-size:14px;letter-spacing:0.3px;border-bottom:2px solid #2BADD4\">Note<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr style=\"border-bottom:1px solid #E8ECF0\">\n<td style=\"padding:12px 16px;font-weight:600;color:#121D36\">J1441<\/td>\n<td style=\"padding:12px 16px;color:#374151\">Injection, filgrastim (G-CSF), 480 mcg<\/td>\n<td style=\"padding:12px 16px;color:#374151\">Neupogen (originator)<\/td>\n<td style=\"padding:12px 16px;color:#374151\">Deleted January 1, 2014<\/td>\n<td style=\"padding:12px 16px;color:#374151\">Do not submit<\/td>\n<\/tr>\n<tr style=\"border-bottom:1px solid #E8ECF0;background:#F9FAFB\">\n<td style=\"padding:12px 16px;font-weight:600;color:#121D36\">J1440 (former)<\/td>\n<td style=\"padding:12px 16px;color:#374151\">Injection, filgrastim (G-CSF), 300 mcg<\/td>\n<td style=\"padding:12px 16px;color:#374151\">Neupogen (originator)<\/td>\n<td style=\"padding:12px 16px;color:#374151\">Deleted January 1, 2014<\/td>\n<td style=\"padding:12px 16px;color:#374151\">Flat-dose code retired with J1441<\/td>\n<\/tr>\n<tr style=\"border-bottom:1px solid #E8ECF0\">\n<td style=\"padding:12px 16px;font-weight:600;color:#121D36\">J1440 (current)<\/td>\n<td style=\"padding:12px 16px;color:#374151\">Fecal microbiota, live-jslm, 1 ml<\/td>\n<td style=\"padding:12px 16px;color:#374151\">Rebyota<\/td>\n<td style=\"padding:12px 16px;color:#374151\">Active<\/td>\n<td style=\"padding:12px 16px;color:#374151\">Unrelated product; never use for filgrastim<\/td>\n<\/tr>\n<tr style=\"border-bottom:1px solid #E8ECF0;background:#F9FAFB\">\n<td style=\"padding:12px 16px;font-weight:600;color:#121D36\">J1442<\/td>\n<td style=\"padding:12px 16px;color:#374151\">Injection, filgrastim (G-CSF), excludes biosimilars, 1 microgram<\/td>\n<td style=\"padding:12px 16px;color:#374151\">Neupogen (Amgen)<\/td>\n<td style=\"padding:12px 16px;color:#374151\">Active<\/td>\n<td style=\"padding:12px 16px;color:#374151\">Primary replacement; units = mcg administered<\/td>\n<\/tr>\n<tr style=\"border-bottom:1px solid #E8ECF0\">\n<td style=\"padding:12px 16px;font-weight:600;color:#121D36\">Q5101<\/td>\n<td style=\"padding:12px 16px;color:#374151\">Injection, filgrastim-sndz, biosimilar, 1 microgram<\/td>\n<td style=\"padding:12px 16px;color:#374151\">Zarxio (Sandoz)<\/td>\n<td style=\"padding:12px 16px;color:#374151\">Active<\/td>\n<td style=\"padding:12px 16px;color:#374151\">Biosimilar-specific code<\/td>\n<\/tr>\n<tr style=\"border-bottom:1px solid #E8ECF0;background:#F9FAFB\">\n<td style=\"padding:12px 16px;font-weight:600;color:#121D36\">Q5110<\/td>\n<td style=\"padding:12px 16px;color:#374151\">Injection, filgrastim-aafi, biosimilar, 1 microgram<\/td>\n<td style=\"padding:12px 16px;color:#374151\">Nivestym (Pfizer)<\/td>\n<td style=\"padding:12px 16px;color:#374151\">Active<\/td>\n<td style=\"padding:12px 16px;color:#374151\">Biosimilar-specific code<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n\n<p class=\"wp-block-paragraph\">One crosswalk error is worth naming, because it appears in several billing articles. J3262 is not a filgrastim code and is not assigned to Nivestym. J3262 describes injection, tocilizumab, 1 mg, the rheumatoid arthritis biologic sold as Actemra. Nivestym (filgrastim-aafi) is billed under Q5110.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">For unit calculation, place-of-service rules, and the ICD-10 pairings that support medical necessity under the replacement code, see our reference on <a href=\"https:\/\/pabau.com\/procedure-codes\/hcpcs-code-j1442\/\">J1442<\/a>. The <a href=\"https:\/\/www.aapc.com\/codes\/hcpcs-codes-range\/\" target=\"_blank\" rel=\"nofollow noopener\">AAPC HCPCS code lookup<\/a> shows current status alongside historical records.<\/p>\n\n\n\n<h2 id=\"h-j1442-vs-j1441-what-changed-for-billers\" class=\"wp-block-heading\">J1442 vs J1441: what changed for billers<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Both codes covered originator filgrastim, and the billing unit is the whole difference. J1441 billed a fixed 480 mcg dose as a single unit. J1442 bills per microgram, so the biller reports the micrograms administered as the quantity.<\/p>\n\n\n\n<table style=\"width:100%;border-collapse:separate;border-spacing:0;border-radius:12px;overflow:hidden;font-size:15px;line-height:1.5;margin:1.5em 0 2em;box-shadow:0 2px 12px rgba(0,0,0,0.08)\">\n<thead>\n<tr>\n<th style=\"background:#121D36;color:#fff;padding:14px 16px;text-align:left;font-weight:600;font-size:14px;letter-spacing:0.3px;border-bottom:2px solid #2BADD4\">Code<\/th>\n<th style=\"background:#121D36;color:#fff;padding:14px 16px;text-align:left;font-weight:600;font-size:14px;letter-spacing:0.3px;border-bottom:2px solid #2BADD4\">Billing unit<\/th>\n<th style=\"background:#121D36;color:#fff;padding:14px 16px;text-align:left;font-weight:600;font-size:14px;letter-spacing:0.3px;border-bottom:2px solid #2BADD4\">Status<\/th>\n<th style=\"background:#121D36;color:#fff;padding:14px 16px;text-align:left;font-weight:600;font-size:14px;letter-spacing:0.3px;border-bottom:2px solid #2BADD4\">Billing logic for a 480 mcg dose<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr style=\"border-bottom:1px solid #E8ECF0\">\n<td style=\"padding:12px 16px;font-weight:600;color:#121D36\">J1442<\/td>\n<td style=\"padding:12px 16px;color:#374151\">Per 1 microgram<\/td>\n<td style=\"padding:12px 16px;color:#374151\">Active<\/td>\n<td style=\"padding:12px 16px;color:#374151\">Bill J1442 x 480 units<\/td>\n<\/tr>\n<tr style=\"border-bottom:1px solid #E8ECF0;background:#F9FAFB\">\n<td style=\"padding:12px 16px;font-weight:600;color:#121D36\">J1441<\/td>\n<td style=\"padding:12px 16px;color:#374151\">Per 480 mcg (flat dose)<\/td>\n<td style=\"padding:12px 16px;color:#374151\">Deleted January 1, 2014<\/td>\n<td style=\"padding:12px 16px;color:#374151\">Bill J1441 x 1 unit (historical claims only)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n\n<p class=\"wp-block-paragraph\">The migration error to watch for is a quantity of 1. Setting up J1442 with one unit bills 1 mcg instead of 480 mcg, which underpays the claim by a factor of 480. When you build the charge for a 480 mcg vial, the quantity must equal the total micrograms administered.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The denominator changes from one J-code to the next. <a href=\"https:\/\/pabau.com\/procedure-codes\/hcpcs-code-j1250\/\">J1250<\/a> bills per 250 mg of dobutamine, while <a href=\"https:\/\/pabau.com\/procedure-codes\/hcpcs-code-j1120\/\">J1120<\/a> covers up to 500 mg of acetazolamide. Read the descriptor before you set the quantity.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Write that logic into the charge entry workflow rather than leaving it to memory. Practices running <a href=\"https:\/\/pabau.com\/blog\/mobile-iv-therapy-business\/\">mobile IV therapy<\/a> face the same quantity-entry risk across every per-microgram J-code they touch.<\/p>\n\n\n\n<h2 id=\"h-filgrastim-biosimilar-hcpcs-codes\" class=\"wp-block-heading\">Filgrastim biosimilar HCPCS codes<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Biosimilar filgrastim reached the US market in 2015 with Zarxio (filgrastim-sndz), and CMS assigns each product its own HCPCS code. Billing the originator code for a biosimilar, or the reverse, creates a drug-to-code mismatch. That mismatch can fail the NDC crosswalk or pull the claim into medical review.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Practices billing injectable biologics through an <a href=\"https:\/\/pabau.com\/industry\/iv-therapy-emr-software\/\">IV therapy EMR<\/a> need to match the dispensed product to its own code. The current filgrastim family looks like this:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>J1442<\/strong>: Injection, filgrastim (G-CSF), excludes biosimilars, 1 microgram. The originator code, used for Neupogen (Amgen) only.<\/li>\n\n\n<li><strong>Q5101<\/strong>: Injection, filgrastim-sndz (Zarxio), biosimilar, 1 microgram. Zarxio was the first biosimilar G-CSF approved in the US.<\/li>\n\n\n<li><strong>Q5110<\/strong>: Injection, filgrastim-aafi (Nivestym), biosimilar, 1 microgram. Nivestym came from Pfizer and Hospira in 2018.<\/li>\n\n\n<li><strong>Q5125<\/strong>: Injection, filgrastim-ayow (Releuko), biosimilar, 1 microgram. Releuko comes from Amneal Pharmaceuticals and Kashiv BioSciences.<\/li>\n\n\n<li><strong>Q5148<\/strong>: Injection, filgrastim-txid (Nypozi), biosimilar, 1 microgram. Nypozi is the Tanvex BioPharma product.<\/li>\n\n\n<li><strong>J1447<\/strong>: Injection, tbo-filgrastim, 1 microgram. Granix (Teva) carries its own code and is never billed under J1442.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">Every code in that list bills per 1 microgram, so the quantity logic is identical across products. Only the code changes when the dispensed product changes. Cross-reference the product NDC against the <a href=\"https:\/\/www.cms.gov\/medicare\/physician-fee-schedule\/search\/overview\" target=\"_blank\" rel=\"nofollow noopener\">CMS Physician Fee Schedule<\/a> before each billing run.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Other injectable biologics use different denominators. <a href=\"https:\/\/pabau.com\/procedure-codes\/hcpcs-code-j0885\/\">J0885<\/a> covers epoetin alfa in 1,000-unit increments, and its biosimilar carries a separate Q code.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"https:\/\/cdn.pabau.com\/cdn\/attachments\/pulse\/content-engine\/billing_codes\/hcpcs-code-j1441\/automate-claims-through-healthcode.webp\" alt=\"Automated insurance claim submission from a patient record\"\/><figcaption class=\"wp-element-caption\"><em>Automated claim submission carries the drug code, quantity, and NDC straight from the administration record.<\/em><\/figcaption><\/figure>\n\n\n\n<div style=\"height:35px;width:800px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 id=\"h-medicare-and-payer-coverage-for-filgrastim\" class=\"wp-block-heading\">Medicare and payer coverage for filgrastim<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Medicare Part B covers filgrastim injections administered incident-to in a physician office or outpatient setting, provided the clinical indication is documented. Covered indications commonly include chemotherapy-induced neutropenia, bone marrow transplant support, and severe chronic neutropenia. Coverage is not automatic, and the medical necessity record has to support the claim.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">CMS program memorandum A02050, issued in 2002, listed Medicare co-pay amounts for J1440 and J1441 while both codes were active. Those figures are more than two decades old and say nothing about current payment. Part B pays injectable drugs at average sales price (ASP) plus 6%, and CMS republishes those rates quarterly.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Pull current rates from the CMS Physician Fee Schedule or from your Medicare Administrative Contractor (MAC) fee schedule, never from an archived transmittal. Commercial payer policy varies. Most follow the Medicare medical necessity framework, and some require prior authorization for outpatient self-administered doses.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/pabau.com\/blog\/do-med-spas-have-to-be-hipaa-compliant\/\">HIPAA-compliant<\/a> documentation of the clinical indication is needed for every payer, with or without prior authorization. Practices using an <a href=\"https:\/\/pabau.com\/templates\/iv-therapy-patient-intake\/\">IV therapy intake<\/a> form should capture that indication in structured fields tied to the billing record.<\/p>\n\n\n\n<h2 id=\"h-documentation-requirements-for-filgrastim-claims\" class=\"wp-block-heading\">Documentation requirements for filgrastim claims<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">A filgrastim claim needs a record that ties the drug to the encounter, the indication, and the exact dose given. Missing any one of those links gives a payer clean grounds to deny on medical necessity or documentation. Keep this minimum set on file for every administration.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Physician order:<\/strong> Dated and signed, naming the drug, dose, route, and frequency.<\/li>\n\n\n<li><strong>Supporting diagnosis:<\/strong> The ICD-10 code documented in the encounter note and linked on the claim.<\/li>\n\n\n<li><strong>Administration record:<\/strong> Date, time, product name, NDC, lot number, micrograms administered, and route.<\/li>\n\n\n<li><strong>Lab results:<\/strong> The absolute neutrophil count supporting the neutropenia or prophylaxis indication.<\/li>\n\n\n<li><strong>Prior authorization:<\/strong> The payer reference number, approval dates, and authorized quantity, where required.<\/li>\n\n\n<li><strong>Waste documentation:<\/strong> The amount discarded when only part of a vial is used, per payer rules.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">Defending a pre-2014 encounter runs on the same record set plus one extra item. Keep the code set that was active on the date of service alongside the original claim. The reviewer can then see that J1441 was valid when it was billed.<\/p>\n\n\n\n<h2 id=\"h-how-to-bill-filgrastim-injections-correctly-today\" class=\"wp-block-heading\">How to bill filgrastim injections correctly today<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">With J1441 retired, the workflow below is the current path for a filgrastim claim. Following it reduces clearinghouse rejections and protects against NDC-to-HCPCS crosswalk failures.<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>Confirm the dispensed product.<\/strong> Identify whether the patient received originator filgrastim (Neupogen) or a biosimilar such as Zarxio, Nivestym, Releuko, or Nypozi. The code follows the specific product, not the drug class.<\/li>\n\n\n<li><strong>Select the correct HCPCS code.<\/strong> Use J1442 for Neupogen, Q5101 for Zarxio, Q5110 for Nivestym, Q5125 for Releuko, or Q5148 for Nypozi. Neither J1440 nor J1441 belongs on a filgrastim claim.<\/li>\n\n\n<li><strong>Set the quantity correctly.<\/strong> Every current filgrastim code bills per 1 microgram, so enter the total micrograms administered. A standard 480 mcg Neupogen dose is J1442 x 480 units.<\/li>\n\n\n<li><strong>Report the NDC.<\/strong> Medicare and many commercial payers require the 11-digit National Drug Code for physician-administered drugs. Take the NDC from the product label, not from a crosswalk assumption.<\/li>\n\n\n<li><strong>Document medical necessity.<\/strong> Record the clinical indication in the patient chart. For Medicare, that means a diagnosis code mapping to a covered filgrastim indication, such as chemotherapy-induced neutropenia.<\/li>\n\n\n<li><strong>Submit the administration code separately.<\/strong> The J-code pays for the drug. The injection itself is billed under CPT 96372 for a subcutaneous or intramuscular dose, or the matching IV push or infusion code. Filgrastim is a growth factor, so the chemotherapy administration codes 96401 to 96549 never apply.<\/li>\n<\/ol>\n\n\n\n<p class=\"wp-block-paragraph\">Practices with an <a href=\"https:\/\/pabau.com\/blog\/best-emr-for-iv-therapy\/\">EMR for IV therapy<\/a> can automate parts of this. NDC capture at the point of administration and a validation rule that rejects J1441 at charge entry are the two highest-value pieces. Catching the code inside the practice costs far less than working the rejection afterward.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Teams <a href=\"https:\/\/pabau.com\/blog\/how-to-open-an-iv-therapy-clinic\/\">opening an IV practice<\/a> or a <a href=\"https:\/\/pabau.com\/industry\/regenerative-medicine-emr\/\">regenerative medicine<\/a> service should build the J-code logic correctly on day one. That beats correcting a year of underbilled claims.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"https:\/\/cdn.pabau.com\/cdn\/attachments\/pulse\/content-engine\/billing_codes\/hcpcs-code-j1441\/prescribe-controlled-drugs-safely-and-stay-compliant.webp\" alt=\"Structured drug prescribing and administration record in a patient chart\"\/><figcaption class=\"wp-element-caption\"><em>Structured prescribing records capture the product, dose, and route that a filgrastim J-code claim has to match.<\/em><\/figcaption><\/figure>\n\n\n\n<div style=\"height:35px;width:800px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n        <div id=\"pro_tip\">\n            <div class=\"img\">\n                <svg width=\"42\" height=\"42\" viewBox=\"0 0 42 42\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\n                    <path fill-rule=\"evenodd\" clip-rule=\"evenodd\"\n                        d=\"M12.6383 19.5238C12.6632 21.2071 12.8734 22.9926 12.0685 24.5523C11.0341 26.8917 8.45076 28.169 7.56292 30.5918C6.63082 33.1061 7.19505 36.185 9.31371 37.9786C10.929 39.5678 13.4183 39.9873 15.6061 39.5463C17.4592 39.073 19.1049 37.8388 19.9706 36.1608C20.781 34.7141 20.7866 32.9904 20.5293 31.3985C20.1006 29.3092 18.3775 27.8705 16.9807 26.362C14.8814 24.1005 14.6684 20.6854 15.595 17.8915C16.4331 15.4768 19.0026 14.2344 20.0425 11.9461C20.7202 10.6769 20.7506 9.20327 20.6068 7.81304C20.1864 5.40098 18.3139 3.23631 15.8716 2.56674C13.9742 2.03969 11.8224 2.30052 10.1739 3.37614C8.70522 4.34688 7.5878 5.86618 7.28356 7.58178C6.76081 9.82981 7.53525 12.2822 9.20307 13.9118C10.7658 15.4741 12.4806 17.2273 12.6383 19.5238Z\"\n                        fill=\"#2BADD4\" \/>\n                    <path fill-rule=\"evenodd\" clip-rule=\"evenodd\"\n                        d=\"M22.7048 19.8387C22.6822 22.3279 24.4507 24.6234 26.7493 25.4682C28.0531 25.961 29.4725 25.9183 30.7989 25.5487C32.0575 24.9955 33.301 24.2237 34.0069 23.0092C34.8384 21.5811 35.2982 19.8286 34.7832 18.2094C34.3611 16.2507 32.8739 14.6541 31.0275 13.9426C28.6736 12.9595 25.8073 13.7942 24.1719 15.7001C23.2022 16.8366 22.6143 18.3326 22.7048 19.8387Z\"\n                        fill=\"#2BADD4\" \/>\n                <\/svg>\n            <\/div>\n            <div class=\"text\">\n                <h3>Pro Tip<\/h3>\n                <p>When you move a patient from Neupogen to a biosimilar, update the HCPCS code in the charge master the same day. Billing J1442 for Zarxio, or Q5101 for Neupogen, creates an NDC-to-code mismatch that can trigger a medical review request. Keep a mapped list of your formulary filgrastim products with their current codes, and review it whenever your supplier changes the dispensed product.<\/p>\n            <\/div>\n        <\/div>\n    \n\n\n<h2 id=\"h-ndc-codes-associated-with-j1441\" class=\"wp-block-heading\">NDC codes associated with J1441<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">While J1441 was active, its associated NDCs corresponded to Neupogen vial presentations manufactured by Amgen. An NDC is an 11-digit identifier assigned by the FDA. It appears on the drug label as labeler code, product code, and package code segments.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">For an audit or appeal covering a pre-2014 encounter, use the NDC-to-HCPCS crosswalk file for that date of service. CMS publishes historical crosswalk files by effective date, mapping each NDC to the code that was active at the time.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Do not apply a current-year crosswalk file to a 2013 claim, because the flat-dose codes were still valid then. A versioned archive of crosswalk files makes those audit responses considerably faster to assemble.<\/p>\n\n\n\n<h2 id=\"h-how-pabau-keeps-retired-j-codes-off-your-claims\" class=\"wp-block-heading\">How Pabau keeps retired J-codes off your claims<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">A retired code such as J1441 sits in the charge master until someone traces the rejections back to it. Quantity logic built for a flat dose keeps underbilling in the meantime.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Practice management software like Pabau keeps the clinical record and the claim in one system. The product, NDC, lot number, and micrograms administered are recorded at the point of care and carried into the charge. Billing staff work from the administration record instead of re-entering it.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Pabau&#8217;s <a href=\"https:\/\/pabau.com\/features\/claims-management-software\/\">claims management software<\/a> validates charges before they leave the practice. A legacy code or a quantity of 1 surfaces internally rather than at the clearinghouse.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/pabau.com\/features\/prescription-management-software\/\">Prescription management software<\/a> handles the structured drug recording behind it, and <a href=\"https:\/\/pabau.com\/blog\/ehr-integration\/\">EHR integration<\/a> removes the manual re-entry that produces quantity errors.<\/p>\n\n\n        <div id=\"book_a_demo\">\n            <div class=\"left-side\">\n                <div class=\"logo\">\n                    <img decoding=\"async\"\n                        src=\"https:\/\/pabau.com\/wp-content\/uploads\/2026\/01\/Logo.svg\"\n                        alt=\"Logo\"\n                        loading=\"lazy\"\n                    \/>\n                <\/div>\n\n                <h3 class=\"heading\">\n                    Catch retired J-codes before the claim goes out                <\/h3>\n\n                <p class=\"description\">\n                    Pabau keeps drug administration records, NDC data, and diagnosis codes on one patient file. Charge validation runs before submission, so filgrastim claims leave your practice clean.                <\/p>\n\n                <div class=\"button-group\">\n                    <a href=\"\/book-demo\/\" class=\"btn btn-scale-effect btn-cta-color btn-md\">\n                        <span class=\"btn-text\">Book a demo<\/span>\n                        <div class=\"btn-icon btn-icon-right\" aria-hidden=\"true\">\n                            <svg\n                                width=\"14\"\n                                height=\"12\"\n                                viewBox=\"0 0 14 12\"\n                                fill=\"none\"\n                                xmlns=\"http:\/\/www.w3.org\/2000\/svg\"\n                            >\n                                <path\n                                    d=\"M0.75 4.77295C0.335786 4.77295 0 5.10874 0 5.52295C0 5.93716 0.335786 6.27295 0.75 6.27295V5.52295V4.77295ZM13.2803 6.05328C13.5732 5.76039 13.5732 5.28551 13.2803 4.99262L8.50736 0.219648C8.21447 -0.073245 7.73959 -0.073245 7.4467 0.219648C7.15381 0.512542 7.15381 0.987415 7.4467 1.28031L11.6893 5.52295L7.4467 9.76559C7.15381 10.0585 7.15381 10.5334 7.4467 10.8263C7.73959 11.1191 8.21447 11.1191 8.50736 10.8263L13.2803 6.05328ZM0.75 5.52295V6.27295L12.75 6.27295V5.52295V4.77295L0.75 4.77295V5.52295Z\"\n                                    fill=\"currentColor\"\n                                ><\/path>\n                            <\/svg>\n                        <\/div>\n                    <\/a>\n                <\/div>\n            <\/div>\n\n            <div class=\"right-side\">\n                <img decoding=\"async\"\n                    src=\"https:\/\/pabau.com\/wp-content\/uploads\/2026\/01\/Home-Page-Concept-4.webp\"\n                    alt=\"Pabau claims management dashboard\"\n                    loading=\"lazy\"\n                \/>\n            <\/div>\n        <\/div>\n        \n\n\n<h2 id=\"h-conclusion\" class=\"wp-block-heading\">Conclusion<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">HCPCS code J1441 has been invalid since January 1, 2014, and any charge master still carrying it is generating rejections on filgrastim claims. The fix is a code swap plus a quantity change. Bill J1442 for originator filgrastim at one unit per microgram, and use the product-specific Q code for each biosimilar.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Two traps sit around that swap. J1440 is not the replacement, because CMS reassigned that number to Rebyota. J3262 is not Nivestym either, since it describes tocilizumab. Nivestym belongs to Q5110.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">For practices billing injectable drugs at volume, Pabau flags legacy codes before submission and keeps administration documentation attached to the claim. <a href=\"https:\/\/pabau.com\/book-demo\/\">Book a demo<\/a> to see how that works on your own filgrastim claims.<\/p>\n\n\n        <div id=\"expert_picks\">\n            <div class=\"header\">\n                                    <img decoding=\"async\" src=\"https:\/\/pabau.com\/wp-content\/uploads\/2025\/11\/Expert-Picks.svg\" alt=\"Continue your research\" height=\"42\" width=\"42\">\n                                <h3>Continue your research<\/h3>\n            <\/div>\n            <div class=\"content\">\n                                                            <div class=\"item\">\n                            <div>\n                                <svg width=\"20\" height=\"27\" viewBox=\"0 0 20 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\n                                    <path\n                                        d=\"M18.6223 14.3857C19.1246 13.8975 19.1246 13.1045 18.6223 12.6162L12.1938 6.36621C11.6915 5.87793 10.8759 5.87793 10.3737 6.36621C9.87143 6.85449 9.87143 7.64746 10.3737 8.13574L14.6125 12.2529H2.28571C1.57455 12.2529 1 12.8115 1 13.5029C1 14.1943 1.57455 14.7529 2.28571 14.7529H14.6085L10.3777 18.8701C9.87545 19.3584 9.87545 20.1514 10.3777 20.6396C10.8799 21.1279 11.6955 21.1279 12.1978 20.6396L18.6263 14.3896L18.6223 14.3857Z\"\n                                        fill=\"#54B2D3\" \/>\n                                <\/svg>\n                            <\/div>\n                            <p><strong>Need to track doses across a course of injections?<\/strong> <a href=\"https:\/\/pabau.com\/templates\/medication-schedule\/\">Medication schedule template<\/a> gives you a dated record of what was given and when.<\/p>\n                        <\/div>\n                                                                                <div class=\"item\">\n                            <div>\n                                <svg width=\"20\" height=\"27\" viewBox=\"0 0 20 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\n                                    <path\n                                        d=\"M18.6223 14.3857C19.1246 13.8975 19.1246 13.1045 18.6223 12.6162L12.1938 6.36621C11.6915 5.87793 10.8759 5.87793 10.3737 6.36621C9.87143 6.85449 9.87143 7.64746 10.3737 8.13574L14.6125 12.2529H2.28571C1.57455 12.2529 1 12.8115 1 13.5029C1 14.1943 1.57455 14.7529 2.28571 14.7529H14.6085L10.3777 18.8701C9.87545 19.3584 9.87545 20.1514 10.3777 20.6396C10.8799 21.1279 11.6955 21.1279 12.1978 20.6396L18.6263 14.3896L18.6223 14.3857Z\"\n                                        fill=\"#54B2D3\" \/>\n                                <\/svg>\n                            <\/div>\n                            <p><strong>Billing another injectable drug from the J-code range?<\/strong> <a href=\"https:\/\/pabau.com\/procedure-codes\/hcpcs-code-j0895\/\">J0895<\/a> shows how the same per-unit quantity rules apply to deferoxamine claims.<\/p>\n                        <\/div>\n                                                                                <div class=\"item\">\n                            <div>\n                                <svg width=\"20\" height=\"27\" viewBox=\"0 0 20 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\n                                    <path\n                                        d=\"M18.6223 14.3857C19.1246 13.8975 19.1246 13.1045 18.6223 12.6162L12.1938 6.36621C11.6915 5.87793 10.8759 5.87793 10.3737 6.36621C9.87143 6.85449 9.87143 7.64746 10.3737 8.13574L14.6125 12.2529H2.28571C1.57455 12.2529 1 12.8115 1 13.5029C1 14.1943 1.57455 14.7529 2.28571 14.7529H14.6085L10.3777 18.8701C9.87545 19.3584 9.87545 20.1514 10.3777 20.6396C10.8799 21.1279 11.6955 21.1279 12.1978 20.6396L18.6263 14.3896L18.6223 14.3857Z\"\n                                        fill=\"#54B2D3\" \/>\n                                <\/svg>\n                            <\/div>\n                            <p><strong>Sending patients home after an infusion visit?<\/strong> <a href=\"https:\/\/pabau.com\/templates\/patient-discharge-form\/\">Patient discharge form<\/a> records the products given and the follow-up the patient needs.<\/p>\n                        <\/div>\n                                                                                <div class=\"item\">\n                            <div>\n                                <svg width=\"20\" height=\"27\" viewBox=\"0 0 20 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\n                                    <path\n                                        d=\"M18.6223 14.3857C19.1246 13.8975 19.1246 13.1045 18.6223 12.6162L12.1938 6.36621C11.6915 5.87793 10.8759 5.87793 10.3737 6.36621C9.87143 6.85449 9.87143 7.64746 10.3737 8.13574L14.6125 12.2529H2.28571C1.57455 12.2529 1 12.8115 1 13.5029C1 14.1943 1.57455 14.7529 2.28571 14.7529H14.6085L10.3777 18.8701C9.87545 19.3584 9.87545 20.1514 10.3777 20.6396C10.8799 21.1279 11.6955 21.1279 12.1978 20.6396L18.6263 14.3896L18.6223 14.3857Z\"\n                                        fill=\"#54B2D3\" \/>\n                                <\/svg>\n                            <\/div>\n                            <p><strong>Want to cut manual re-entry between notes and claims?<\/strong> <a href=\"https:\/\/pabau.com\/blog\/ehr-integration\/\">EHR integration<\/a> explains how connected workflows reduce quantity-entry errors on drug claims.<\/p>\n                        <\/div>\n                                                <\/div>\n        <\/div>\n    \n\n\n<h2 id=\"h-frequently-asked-questions\" class=\"wp-block-heading\">Frequently asked questions<\/h2>\n\n\n\n<div class=\"schema-faq wp-block-yoast-faq-block\"><div class=\"schema-faq-section\" id=\"faq-question-1786603734565\"><h3 class=\"schema-faq-question\">What is HCPCS code J1441?<\/h3> <p class=\"schema-faq-answer\">HCPCS code J1441 is a deleted HCPCS Level II J-code. It described an injection of filgrastim (granulocyte colony-stimulating factor, G-CSF) at a flat dose of 480 mcg. Practices used it to bill outpatient administration of originator filgrastim (Neupogen) until CMS removed it from the code set on January 1, 2014.<\/p> <\/div> <div class=\"schema-faq-section\" id=\"faq-question-1786603734566\"><h3 class=\"schema-faq-question\">Is J1441 a deleted HCPCS code?<\/h3> <p class=\"schema-faq-answer\">Yes. CMS deleted J1441 effective January 1, 2014, in the annual HCPCS Level II update. December 31, 2013 was the last valid date of service. Submitting J1441 on a current claim produces a clearinghouse rejection, because the code is absent from the active CMS HCPCS file.<\/p> <\/div> <div class=\"schema-faq-section\" id=\"faq-question-1786603734567\"><h3 class=\"schema-faq-question\">What replaced HCPCS code J1441?<\/h3> <p class=\"schema-faq-answer\">J1442 replaced it. The descriptor is injection, filgrastim (G-CSF), excludes biosimilars, 1 microgram, so a 480 mcg Neupogen dose is billed as J1442 with 480 units. Biosimilars keep their own codes, including Q5101 for Zarxio and Q5110 for Nivestym.<\/p> <\/div> <div class=\"schema-faq-section\" id=\"faq-question-1786603734568\"><h3 class=\"schema-faq-question\">How does J1441 relate to J1440?<\/h3> <p class=\"schema-faq-answer\">J1440 was the sister flat-dose code, covering 300 mcg of filgrastim, and CMS deleted it in the same January 2014 action. Neither is a filgrastim code today. CMS has reassigned the J1440 number to Rebyota (fecal microbiota, live-jslm, 1 ml), an unrelated product.<\/p> <\/div> <div class=\"schema-faq-section\" id=\"faq-question-1786603734569\"><h3 class=\"schema-faq-question\">Is J3262 the HCPCS code for Nivestym?<\/h3> <p class=\"schema-faq-answer\">No. J3262 describes injection, tocilizumab, 1 mg, the rheumatoid arthritis biologic sold as Actemra. Nivestym (filgrastim-aafi) is billed under Q5110. Some crosswalk write-ups pair J3262 with Nivestym in error, so verify the assignment against the current CMS HCPCS file.<\/p> <\/div> <div class=\"schema-faq-section\" id=\"faq-question-1786603734570\"><h3 class=\"schema-faq-question\">Does Medicare cover filgrastim injections?<\/h3> <p class=\"schema-faq-answer\">Yes. Medicare Part B covers filgrastim injections administered incident-to in outpatient settings when medical necessity is documented. Covered indications typically include chemotherapy-induced neutropenia, bone marrow transplant support, and severe chronic neutropenia. Payment follows average sales price (ASP) plus 6%, and CMS updates those rates quarterly.<\/p> <\/div> <div class=\"schema-faq-section\" id=\"faq-question-1786603734571\"><h3 class=\"schema-faq-question\">When was J1441 deleted from the HCPCS code set?<\/h3> <p class=\"schema-faq-answer\">J1441 was deleted effective January 1, 2014, as part of the annual HCPCS Level II update announced in late 2013. No mid-year 2019 update affected the code, despite claims to the contrary in some billing write-ups. The deletion moved filgrastim billing from flat doses to per-microgram units.<\/p> <\/div> <div class=\"schema-faq-section\" id=\"faq-question-1786603734572\"><h3 class=\"schema-faq-question\">Which CPT code covers the filgrastim injection itself?<\/h3> <p class=\"schema-faq-answer\">Use CPT 96372 for a subcutaneous or intramuscular filgrastim injection, and the matching IV push or infusion code when the drug is given intravenously. Filgrastim is a growth factor rather than a chemotherapy agent, so the chemotherapy administration codes 96401 to 96549 do not apply. The J-code covers the drug, and the CPT code covers the administration.<\/p> <\/div> <\/div>\n\n","protected":false},"excerpt":{"rendered":"<p>HCPCS code J1441 described an injection of filgrastim (granulocyte colony-stimulating factor, G-CSF) at a flat dose of 480 mcg. Filgrastim stimulates neutrophil production in patients receiving chemotherapy, undergoing bone marrow transplant, or living with severe chronic neutropenia. Neupogen (Amgen) was the originator brand billed under this code. The code is no longer valid. CMS deleted [&hellip;]<\/p>\n","protected":false},"author":82,"featured_media":177310,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_yoast_wpseo_linkdex":"83","_yoast_wpseo_content_score":"30","_yoast_wpseo_is_cornerstone":"","_yoast_wpseo_keywordsynonyms":"[\"\",\"\",\"\",\"\"]","_yoast_wpseo_focuskw_text_input":"","_seo_original_html":"","footnotes":""},"categories":[1433,1548],"tags":[3898,2957,1611,2953],"class_list":["post-177318","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-billing-codes","category-hcpcs","tag-biologic-injection-billing","tag-drug-administration-billing","tag-hcpcs-codes","tag-j-code-billing"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.2 (Yoast SEO v28.2) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>HCPCS code J1441: deleted code, bill J1442 instead<\/title>\n<meta name=\"description\" content=\"CMS deleted HCPCS code J1441 on January 1, 2014. Bill originator filgrastim as J1442 x 480 units, and each biosimilar under its own Q code.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pabau.com\/nl\/procedure-codes\/hcpcs-code-j1441\/\" \/>\n<meta property=\"og:locale\" content=\"nl_NL\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"HCPCS code J1441: deleted code, bill J1442 instead\" \/>\n<meta property=\"og:description\" content=\"CMS deleted HCPCS code J1441 on January 1, 2014. Bill originator filgrastim as J1442 x 480 units, and each biosimilar under its own Q code.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/pabau.com\/nl\/procedure-codes\/hcpcs-code-j1441\/\" \/>\n<meta property=\"og:site_name\" content=\"Pabau\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/Pabau\/\" \/>\n<meta property=\"article:published_time\" content=\"2026-08-13T11:00:50+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-08-13T12:26:15+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/pabau.com\/wp-content\/uploads\/2026\/08\/hcpcs-code-j1441.webp\" \/>\n\t<meta property=\"og:image:width\" content=\"1200\" \/>\n\t<meta property=\"og:image:height\" content=\"630\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/webp\" \/>\n<meta name=\"author\" content=\"Maja Popovska\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@pabaucrm\" \/>\n<meta name=\"twitter:site\" content=\"@pabaucrm\" \/>\n<meta name=\"twitter:label1\" content=\"Geschreven door\" \/>\n\t<meta name=\"twitter:data1\" content=\"Maja Popovska\" \/>\n\t<meta name=\"twitter:label2\" content=\"Geschatte leestijd\" \/>\n\t<meta name=\"twitter:data2\" content=\"11 minuten\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/pabau.com\\\/nl\\\/procedure-codes\\\/hcpcs-code-j1441\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/pabau.com\\\/nl\\\/procedure-codes\\\/hcpcs-code-j1441\\\/\"},\"author\":{\"name\":\"Maja Popovska\",\"@id\":\"https:\\\/\\\/pabau.com\\\/nl\\\/#\\\/schema\\\/person\\\/b00aec1dd379f0ddcf6137d78e2a21db\"},\"headline\":\"HCPCS code J1441: Filgrastim (G-CSF) 480 mcg injection guide\",\"datePublished\":\"2026-08-13T11:00:50+00:00\",\"dateModified\":\"2026-08-13T12:26:15+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/pabau.com\\\/nl\\\/procedure-codes\\\/hcpcs-code-j1441\\\/\"},\"wordCount\":2588,\"publisher\":{\"@id\":\"https:\\\/\\\/pabau.com\\\/nl\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/pabau.com\\\/nl\\\/procedure-codes\\\/hcpcs-code-j1441\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/pabau.com\\\/wp-content\\\/uploads\\\/2026\\\/08\\\/hcpcs-code-j1441.webp\",\"keywords\":[\"Biologic Injection Billing\",\"Drug Administration Billing\",\"Hcpcs Codes\",\"J Code Billing\"],\"articleSection\":[\"Billing Codes\",\"HCPCS\"],\"inLanguage\":\"nl-NL\"},{\"@type\":[\"WebPage\",\"FAQPage\"],\"@id\":\"https:\\\/\\\/pabau.com\\\/nl\\\/procedure-codes\\\/hcpcs-code-j1441\\\/\",\"url\":\"https:\\\/\\\/pabau.com\\\/nl\\\/procedure-codes\\\/hcpcs-code-j1441\\\/\",\"name\":\"HCPCS code J1441: deleted code, bill J1442 instead\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/pabau.com\\\/nl\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/pabau.com\\\/nl\\\/procedure-codes\\\/hcpcs-code-j1441\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/pabau.com\\\/nl\\\/procedure-codes\\\/hcpcs-code-j1441\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/pabau.com\\\/wp-content\\\/uploads\\\/2026\\\/08\\\/hcpcs-code-j1441.webp\",\"datePublished\":\"2026-08-13T11:00:50+00:00\",\"dateModified\":\"2026-08-13T12:26:15+00:00\",\"description\":\"CMS deleted HCPCS code J1441 on January 1, 2014. 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The deletion moved filgrastim billing from flat doses to per-microgram units.","inLanguage":"nl-NL"},"inLanguage":"nl-NL"},{"@type":"Question","@id":"https:\/\/pabau.com\/nl\/procedure-codes\/hcpcs-code-j1441\/#faq-question-1786603734572","position":8,"url":"https:\/\/pabau.com\/nl\/procedure-codes\/hcpcs-code-j1441\/#faq-question-1786603734572","name":"Which CPT code covers the filgrastim injection itself?","answerCount":1,"acceptedAnswer":{"@type":"Answer","text":"Use CPT 96372 for a subcutaneous or intramuscular filgrastim injection, and the matching IV push or infusion code when the drug is given intravenously. Filgrastim is a growth factor rather than a chemotherapy agent, so the chemotherapy administration codes 96401 to 96549 do not apply. The J-code covers the drug, and the CPT code covers the administration.","inLanguage":"nl-NL"},"inLanguage":"nl-NL"}]}},"yoast":{"focus_keyword":"HCPCS code J1441","seo_title":"HCPCS code J1441: deleted code, bill J1442 instead","meta_description":"CMS deleted HCPCS code J1441 on January 1, 2014. Bill originator filgrastim as J1442 x 480 units, and each biosimilar under its own Q code.","content_score":"30","is_cornerstone":"","related_keyphrases":[{"keyword":"filgrastim g-csf hcpcs","score":72},{"keyword":"hcpcs j1440 j1441","score":61},{"keyword":"filgrastim biosimilar hcpcs code","score":67}]},"_links":{"self":[{"href":"https:\/\/pabau.com\/nl\/wp-json\/wp\/v2\/posts\/177318","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pabau.com\/nl\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pabau.com\/nl\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pabau.com\/nl\/wp-json\/wp\/v2\/users\/82"}],"replies":[{"embeddable":true,"href":"https:\/\/pabau.com\/nl\/wp-json\/wp\/v2\/comments?post=177318"}],"version-history":[{"count":4,"href":"https:\/\/pabau.com\/nl\/wp-json\/wp\/v2\/posts\/177318\/revisions"}],"predecessor-version":[{"id":179715,"href":"https:\/\/pabau.com\/nl\/wp-json\/wp\/v2\/posts\/177318\/revisions\/179715"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pabau.com\/nl\/wp-json\/wp\/v2\/media\/177310"}],"wp:attachment":[{"href":"https:\/\/pabau.com\/nl\/wp-json\/wp\/v2\/media?parent=177318"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pabau.com\/nl\/wp-json\/wp\/v2\/categories?post=177318"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pabau.com\/nl\/wp-json\/wp\/v2\/tags?post=177318"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}